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Senior Software Developer – Web based Technologies

BioHybrid Solutions LLC

This is a Full-time position in Pittsburgh, PA posted March 4, 2021.

nnBioHybrid Solutions LLC (BHS) is a Carnegie Mellon University spin-off, focused on next generation protein-polymer therapeutics as alternatives to PEGylation.

We are a fast-growing company with a network of committed partners and collaborators.

We are looking for an ambitious and motivated candidate for a role of Senior (Principal) Scientist.

The Senior (Principal) Scientist will bring a proven track record with supporting protein therapeutic development from target nomination and preclinical studies to FDA clinical trials.

nn nn Job Description nn nnBioHybrid Solutions (BHS) is looking for a Senior (Principal) Scientist with expertise in enzymology and biochemistry for therapeutic development.nn Support and lead preclinical protein therapeutic development and apply knowledge of the fundamental biopharmaceutical principles of developing biologic drug product.

Develop biochemical assays suitable for HTS, enzyme kinetics and mechanistic studies.

Set up assays to characterize enzyme function, reaction phenotyping, and drug-drug interaction potential for drug candidates.

Develop and optimize downstream processing purification techniques on biological drug substances.

Develop and optimize formulation studies for biological drug products.

Develop and execute stability studies on therapeutic protein variants.

Provide enzymology and biochemistry expertise to internal programs and external collaborators.

Continuously optimize and validate assays as projects evolve from preclinical animal studies to FDA approved clinical trials.

nn Required Qualifications: nn nn PhD with 8 or more years of experience in enzymology, biochemistry, biophysics and/or pharmacology is required.nn Experience in Enzyme Kinetics, Drug Metabolism, or Pharmacokinetics Experience in the development of biochemical assays is required.

Experience with method validation and statistical outcomes.

Extensive experience and knowledge in a majority of the following areas: enzyme characterization, steady-state kinetics and protein biochemistry is required.

Excellent written and oral communication skills is required.

Proficient computer skills and ability to learn new software and systems.

Well organized and methodical.

Flexible in adjusting priorities and able to take risks to accomplish goals.

Ability to effectively communicate expectations.

Ability to gain acceptance of an idea, plan, or activity.

Capable of being a scientific leader with the ability to drive innovation, lead projects and teams, solve complex technical problems and work independently as well as in cross-functional teams.

Ability to initiate and implement new research ideas.

Summarize research results into scientific presentation and manuscript.

Industry experience that is familiar with Good Laboratory Practices (GLP) and/or current Good Manufacturing Practices (cGMP) is a plus nn nn nnBioHybrid Solutions is an equal opportunity employer without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status or any other applicable federal or state protected classification.nn nn n nn nnSend resume to .nn nnby Jobblenn